By the way CFP 3 is working well with most people including everyone I know, but judging from the Comodo forums it seems there are some bugs that may cause problems in particular configurations. They weren't caught before the release because none of the beta testers had the conflictive setups. So it may be a good idea to wait for an update or two, althout for me and most people it's working okay. You can always do a system restore or a bakcup image.
Also you can resort to the Comodo forums for all questions including P2P etc. Since it's a free product, support is provided in the forums --and I'll say that it works way better than a dedicated hotline anyway.
By the way my current security setup is:
Firewall and HIPS: Comodo Firewall Pro 3 with Defense+.
Resident antimalware: Avira AntiVir, Comdo BOClean.
On demand scanners installed: AVG AntiSpyware, Kaspersky online.
Everything free. There are other free self-contained (no installation) scanners such as CureIt!, I haven't used any but they may come handy some day. Also I run Windows as limited user and everything (JavaScript etc.) is blocked by default in the browser except for trusted sites. Actually I've never got infected (*crosses fingers*).
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